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Cytokine Production Testing

Diagram showing interactions between NK cells, T cells, macrophages, and dendritic cells during immune response.

The balance between different cytokines is a crucial aspect of immune regulation, influencing the predominantly pro- and anti-inflammatory immune responsiveness. Understanding whether a natural product induces or inhibits cytokine production in cell-based testing systems can greatly aid in developing a comprehensive portfolio on mechanisms of action. 


NIS Labs conducts testing for a panel of cytokines by utilizing cell culture supernatants from five-day cultures of peripheral blood mononuclear cells that are exposed to test products. To evaluate both direct and synergistic effects, cells are treated with a test product alone and in conjunction with the known T cell mitogen PHA.

Th1 cytokines:

IL-2, TNF-alpha, and Interferon-gamma are crucial components in cell-based testing, as they play significant roles in cytokine production and immune regulation.

Th2 cytokines

Our IoT solutions can help you monitor and manage city infrastructure in real time, enhancing services such as traffic management and waste disposal. By integrating cell-based testing methods, we can optimize cytokine production and improve immune regulation, providing you with the tools needed to make your city more efficient and sustainable.

Next-Generation Healthcare Technologies

The cytokine production of IL-4, IL-6, and IL-10 plays a crucial role in immune regulation, especially when assessed through cell-based testing.

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