Project Tag: CAP-e

15 posts

Antioxidant and Immune-Modulatory Effects of Aloe vera Decolorized Leaf Juice vs. Inner Leaf Juice

The aloe vera (Aloe vera) plant has a long history of traditional therapeutic topical use. Its leaf and inner leaf juices are also ingested in various forms. Aloe vera leaf juice is made from macerated aloe leaves, and when it is intended for human ingestion, it is purified of latex […]

Antioxidant, anti-inflammatory, anti-apoptotic, and skin regenerative properties of an Aloe vera-based extract of Nerium oleander leaves (NAE-8®)

Abstract Objective: The goal for this study was to evaluate the effects of an Aloe vera-based Nerium oleander extract (NAE-8®), compared to an extract of A. vera gel alone (ALOE), and to an aqueous extract of N. oleander (AQ-NOE) in bioassays pertaining to dermatologic potential with respect to antioxidant protection, […]

Antioxidant and Anti-Inflammatory Properties of an Aqueous Cyanophyta Extract Derived from Arthrospira Platensis: Contribution to Bioactivities by the Non-Phycocyanin Aqueous Fraction.

Abstract The goal for this work was to characterize basic biological properties of a novel Arthrospira platensis-based aqueous cyanophyta extract (ACE), enriched in the known anti-inflammatory cyclooxygenase-2 (COX-2) inhibitor phycocyanin (PC), but also containing a high level of non-PC bioactive compounds. Antioxidant properties were tested in parallel in the Folin-Ciocalteu […]

Phenolic acids of the two major blueberry species in the US market and their antioxidant and anti-inflammatory activities.

Abstract Highbush (cultivated) and lowbush (wild) are the two major blueberry species in the US market. Eight phenolic acids were detected and quantified from these two species by HPLC-MS. Chlorogenic acid was found to be the predominant phenolic acid in both species, with 0.44 mg/g fresh weight in lowbush blueberries and […]

Consumption of dried apple peel powder increases joint function and range of motion.

Abstract The goal for this study was to evaluate the effects of consumption of dried apple peel powder (DAPP) on joint function and range of motion (ROM). Additional in vitro and clinical testing was performed to suggest specific mechanisms of action. An open-label clinical pilot study involved 12 healthy people […]

In vitro and ex-vivo cellular antioxidant protection and cognitive enhancing effects of an extract of Polygonum minus Huds (Lineminus™) demonstrated in a Barnes Maze animal model for memory and learning.

Abstract BACKGROUND: Polygonum minus a culinary flavouring that is common in South East Asian cuisine and as a remedy for diverse maladies ranging from indigestion to poor eyesight. The leaves of this herb have been reported to be high in antioxidants. Flavonoids which have been associated with memory, cognition […]

Analgesic and anti-inflammatory properties of a phycocyanin-enriched microalgae extract CyaninPlus.

Objective and methodology The objective for this research was to document the anti-inflammatory  properties Of the microalgae extract in vitro and in vivo. A panel of in vitro tests addressed the following: Antioxidant capacity Inhibition of inflammatory enzymes COX-2 and Lipoxygenase Reduction of free radical production by inflammatory cells Two […]

Antioxidant bioavailability and rapid immune-modulating effects after consumption of a single acute dose of a high-metabolite yeast immunogen: results of a placebo-controlled double-blinded crossover pilot study.

The objective of this pilot study was to investigate the acute effects on circulating lymphocyte subsets, antioxidant status, and cytokine profile after consumption of EpiCor(®) (EP) (Embria Health Sciences, Ankeny, IA, USA), a dried fermentate produced from Saccharomyces cerevisiae, using a placebo-controlled randomized crossover study design with 12 healthy adult […]

Evaluation of bioavailability of antioxidants in EpiCor at the cellular level and in clinical studies, using the cell-based antioxidant protection of erythrocytes (CAP-e) bioassay

Purpose of the study The objective of this study was to evaluate EpiCor» antioxidant bioavailability.  One aspect of bioavailability is to examine whether compounds are capable of crossing the cell membrane and entering live cells. Performing cell-based testing for antioxidant protection involves the dynamics Of living cells, their enzymes, and membrane […]

Açai (Euterpe oleracea) An Amazonian Palm Fruit with Broad Antioxidant and Anti-Inflammatory Activities

The pulp of the Amazonian palm fruit, açai (Euterpe oleracea Mart.), has been found to have exceptional antioxidant capacity in vitro, particularly against the superoxide, peroxyl, and hydroxyl radicals. Studying foods for their potential health benefits to humans can benefit fromin vitro assays that can correlate with in vivo outcomes. […]