The CAP-e assay (Cell-based Antioxidant Protection in Erythrocytes) is a new method for evaluating the antioxidant potential of natural products based on the concept that many such antioxidant products are only of biological relevance if they are able to protect living cells. In other words, it is a cell-based assay for the evaluation of whether antioxidants in natural products are capable of protecting live cells from oxidative damage – it is designed to measure the antioxidant bioavailability of a product at a cellular level.
Herbal ingredient BioPM-101, developed and produced by Biotropics Malaysia Berhad, has been shown to protect live cells from oxidative damage, according to an award-winning test developed by NIS Labs.
The list of tests available to assess antioxidant activity may look like a page ripped from a World War II code book, but understanding how the results are complementary is vital for the continued success of antioxidants.
NIS Labs, Klamath Falls, OR, is a contract research laboratory that evaluates strategies to improve immune function and reduce inflammation, hence the name Natural Immune Systems, or NIS for short. Over the years, according to Gitte Jensen, PhD, research director, the company’s mission and research goals have evolved. “Today, a good part of what we do involves testing natural products in different cellular testing protocols, in contrast to chemical or analytical testing—much of this work assists our clients by providing the foundation behind mechanisms of action claims,” she said. “We believe we have a unique skill set to offer this growing industry: Solid academic research training, combined with an understanding of the special demands to research protocols necessary when working with complex natural products.” – See more