In The News

Study Demonstrates Cyactiv’s Antioxidant and Anti-Inflammatory Support

A study recently published in the Journal of Medicinal Food (Jensen et al.) set out to characterize the basic biological properties of Cyactiv, which contains a known anti-inflammatory cyclooxygenase-2 (COX-2) inhibitor phycocyanin (PC), as well as a high level of non- phycocyanin bioactive compounds.

Read more

Top 10 articles downloaded from JMF.

We are happy to inform you that your article entitled, “Consumption of Dried Apple Peel Powder Increases Joint Function and Range of Motion”, has been ranked in the Top 10 articles downloaded from the Journal of Medicinal Food official website.

Certificate (J Med Food 17 (11) 2014, 1204-1213)

Recognizing the potential return on investing in research, and the potential cost of lacking clinical validation for products, more nutraceutical companies are partnering with contract research organizations (CROs) to prove new concepts, substantiate existing claims or differentiate unique product formulas.

Historically, the nutraceutical industry has relied heavily on “borrowed science,” noted Gitte Jensen, PhD, research director, NIS Labs, Klamath Falls, OR. However, more companies are conducting their own clinical studies to strengthen marketing claims and reinforce their regulatory standing.

Read More

Patent Granted on CAP-e (Cell-based antioxidant protection) assay

The CAP-e assay (Cell-based Antioxidant Protection in Erythrocytes) is a new method for evaluating the antioxidant potential of natural products based on the concept that many such antioxidant products are only of biological relevance if they are able to protect living cells. In other words, it is a cell-based assay for the evaluation of whether antioxidants in natural products are capable of protecting live cells from oxidative damage – it is designed to measure the antioxidant bioavailability of a product at a cellular level.

Controversies continue to surround methods of testing and measuring antioxidant activity.

Has there been too much hype over antioxidants in recent years? Why did the USDA remove the Oxygen Radical Absorbance Capacity (ORAC) database last year? And how can we help our industry reach a grounded and solid understanding of the true value of antioxidants?

The chemical proof that a product contains compounds that will interfere with specific oxidizing chemical reactions drove parts of our industry into a numbers game: “My ORAC is bigger than yours.”  This was related to some confusion between antioxidants and biologically active compounds. The USDA wrote this when it withdrew the ORAC database from public view: “We know now that antioxidant molecules in food have a wide range of functions, many of which are unrelated to the ability to absorb free radicals.” Whether this fact is a good reason to withdraw the ORAC database from the public domain remains debatable.- See more


NIS Labs’ CAP-e Assay Evaluates Cellular Antioxidant Protection

Herbal ingredient BioPM-101, developed and produced by Biotropics Malaysia Berhad, has been shown to protect live cells from oxidative damage, according to an award-winning test developed by NIS Labs.

Read More

Cracking the code on antioxidant testing

The list of tests available to assess antioxidant activity may look like a page ripped from a World War II code book, but understanding how the results are complementary is vital for the continued success of antioxidants.

Read more

NIS Labs’ CAP-e Bioassay Wins INSIDER Scientific Excellence Award

NIS Labs’ CAP-e Bioassay Wins INSIDER Scientific Excellence Award

PHOENIX—Virgo Publishing announced this week that NIS Labs’ new biological assay CAP-e (Cell-based Antioxidant Protection in Erythrocytes) will receive the INSIDER Scientific Excellence Award, presented at SupplySide West, Oct. 22 to 24 in Las Vegas.


Ingredient suppliers and technology providers with new ingredient/technology science, a new application, or any research-based breakthrough in ingredient/technology science, submitted applications for the award. A panel of judges comprised of R&D and product development professionals from leading supplement manufacturing companies evaluated the submissions on science/research methods, science breakthrough, innovation and appeal for the manufacturing community.

CAP-e is used for evaluating the antioxidant potential of natural products and assesses whether antioxidants are capable of penetrating and protecting live cells from oxidative damage. The assay answers the question of bioavailability at the cellular level, and was specifically developed to assist the transition of analytical chemistry testing of natural products into biological assays in vitro and in vivo.  More information is available at

The award will be presented to NIS Labs at 2pm in the Virgo Publishing booth, #20051, on Friday, Oct. 24. The inside cosmeceuticals Scientific Excellence Award and the Food Product Design Award, given to Nutragenesis’ Sensara™ and DSM Food Ingredients for PreventASe,™ respectively, will be awarded at the same time.

Read More